ceesdekker.net Fundamentals Explained
ceesdekker.net Fundamentals Explained
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2009, discovery of a completely new phenotype for microbes in narrow nanofluidic slits; and initial detection of nearby protein structures along DNA utilizing sound-condition nanopores
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
Dynamics of initiation, termination and reinitiation of DNA translocation through the motor protein EcoR124I
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and initially ever analyze on the dynamics DNA supercoils and the discovery of supercoil hopping
The coiled-coil from the human Rad50 DNA repair service protein incorporates specific segments of amplified adaptability
We shape germs into varieties that deviate from their pure phenotype. Precisely, I'll demonstrate our capability to shape live E. coli microbes into novel designs including rectangles, squares, triangles and circles.
He also uncovered time to write down quite a few publications, send out Nearly forty thousand tweets and direct a successful analysis team at Delft College of Technological innovation. ‘It doesn’t experience like perform’, he suggests. ‘I’m just terribly curious.’
In 1993, like a younger and keen affiliate professor at Delft University of Engineering, I'd in the beginning focused the analysis initiatives of my team on measuring the electrical conductance of only one conducting-polymer molecule. Inside two a long time, we experienced made a tool by which just one wire of a phthalocyaninepolysiloxane polymer was linked involving two intently spaced metallic nanoelectrodes.
Resolving the phase dimension in condensin-driven DNA loop extrusion identifies ATP binding because the step-generating process
An built-in microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes
Many new phenomena ended up identified, and he and his research group established a leading position In this particular field of exploration. Dekker and his investigation group uncovered new physics of nanotubes as well https://www.ceesdekker.net as explored the feasibility of molecular electronics. In 1998, they ended up the first to develop a transistor according to one nanotube molecule.
As an example, we look at the nucleopore advanced, a gateway amongst the cell nucleus as well as cytoplasm. This is an extremely complex system and for that reason tough to study inside of a cell, so we use biomimetics. We reconstruct holes and then insert particular person factors of the nucleopore complex to review transport by it at the single-molecule stage.’
2013, managed shaping of live bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations in the handedness of histone tetrasomes